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侵入的压力:氯氮卓的减轻作用。

The stress of intruding: reduction by chlordiazepoxide.

作者信息

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出版信息

Physiol Behav. 1984 Sep;33(3):345-7. doi: 10.1016/0031-9384(84)90152-5.

DOI:10.1016/0031-9384(84)90152-5
PMID:6542680
Abstract

Rats placed as intruders in a long-established colony showed significant elevations of plasma corticosterone after 10-20 minutes of intruding. This rise was prevented by 5 days pretreatment with chlordiazepoxide (5 mg/kg). The rats resident in the colony had significantly higher basal corticosterone concentrations compared with singly housed rats but the same as rats housed in groups of six in a normal cage. The resident rats showed no elevation of plasma corticosterone in response to 20 minutes of an intruder in the colony.

摘要

作为入侵者被放入一个长期存在的鼠群中的大鼠,在侵入10 - 20分钟后,血浆皮质酮显著升高。这种升高可通过氯氮卓(5毫克/千克)预处理5天来预防。与单独饲养的大鼠相比,鼠群中的常驻大鼠基础皮质酮浓度显著更高,但与正常笼子中6只一组饲养的大鼠相同。常驻大鼠在面对鼠群中有入侵者20分钟时,血浆皮质酮没有升高。

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