Roux J, Baudon D, Robert V, Stanghellini A, Gazin P, Lhuillier M, Saluzzo J F, Cornet M, Sarthou J L, Molez J F
Med Trop (Mars). 1984 Oct-Dec;44(4):303-9.
An epidemic of yellow fever raged during the last three months of 1983 in South East of Upper Volta. It spread on about ten thousand square kilometers, in a bushy savanna area, affecting only populations living in contact with forest galleries, belonging especially to the peul ethnical group. The transmission of the virus was effected by sylvatic vectors, essentially Aedes furcifer. Serological tests showed that about 50 % of the population living in contact with forest galleries was affected, that is to say 15.000 to 17.500 people. The average death rate on the whole area was 4 % (800 to 1.700 deaths); the lethality rate was estimated between 6 and 10 % of affected people. On the whole, 54 strains of yellow fever virus were isolated from human blood samples, and 26 strains from batches of mosquitoes. We called this epidemic "intermediate sylvatic epidemic". The epidemic quickly decreased in the sylvatic area, owing to climatic conditions. A mass campaign of vaccinations prevented it from spreading to near urban centres. On this particular case, the thermostability on field of the vaccine 17D provided by the Institute Pasteur of Dakar was proved to be effective.
1983年最后三个月,上沃尔特东南部爆发了一场黄热病疫情。疫情在约一万平方公里的灌木稀树草原地区蔓延,仅影响与森林廊道有接触的人群,这些人群主要属于富拉尼族。病毒通过野生媒介传播,主要是非洲伊蚊。血清学检测表明,约50%与森林廊道有接触的人群受到感染,即15000至17500人。整个地区的平均死亡率为4%(800至1700人死亡);致死率估计在受感染人群的6%至10%之间。总体而言,从人类血液样本中分离出54株黄热病毒,从一批蚊子中分离出26株。我们将此次疫情称为“中间型野生型疫情”。由于气候条件,疫情在野生区域迅速减弱。大规模疫苗接种运动防止了疫情蔓延至附近城市中心。在这个特殊案例中,达喀尔巴斯德研究所提供的17D疫苗在野外的热稳定性被证明是有效的。