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1976年至1980年塞内加尔的黄热病(作者译)

[Yellow fever in Senegal from 1976 to 1980 (author's transl)].

作者信息

Salaun J J, Germain M, Robert V, Robin Y, Monath T P, Camicas J L, Digoutte J P

出版信息

Med Trop (Mars). 1981 Jan-Feb;41(1):45-51.

PMID:6792455
Abstract

The isolation of a YF strain in Kedougou (eastern region) in December 1976 from Aedes gr. furcifer taylori lead to a mass vaccination campaign in Senegal. In 1977, 67 strains were isolated from different mosquitoes (essentially A. luteocephalus and A. gr. furcifer taylori). Among these strains, 3 were isolated from males and this very important phenomenon might explain the virus conservation during the dry season. In 1978, 55 strains were isolated from mosquitoes of the same species, but not from males, and five from monkeys (E. patas and C. aethiops). But no increase of morbidity or mortality was observed in humans. In December 1978, a YF outbreak occurred in the Gambia with 271 suspect cases and 63 deaths; 2 strains were isolated from A. aegypti. In 1979, the epidemic seemed to have disappeared. Up to now, one single strain has been isolated from mosquitoes. But danger remains, and 3 YF human cases with 2 deaths were observed in Sine-Saloum, among French unvaccinated tourists.

摘要

1976年12月在凯杜古(东部地区)从黄带黑背蚊中分离出一株黄热病病毒株,这导致了塞内加尔的大规模疫苗接种运动。1977年,从不同蚊子(主要是黄头伊蚊和黄带黑背蚊)中分离出67株病毒。在这些毒株中,有3株是从雄性蚊子中分离出来的,这一非常重要的现象可能解释了旱季期间病毒的保存情况。1978年,从同一种类的蚊子中分离出55株病毒,但不是从雄性蚊子中分离的,还有5株是从猴子(草原狒狒和埃塞俄比亚长尾猴)中分离出来的。但未观察到人类发病率或死亡率上升。1978年12月,冈比亚发生黄热病疫情,有271例疑似病例,63人死亡;从埃及伊蚊中分离出2株病毒。1979年,疫情似乎已经消失。到目前为止,仅从蚊子中分离出一株病毒。但危险仍然存在,在锡内-萨卢姆,在未接种疫苗的法国游客中观察到3例黄热病病例,2人死亡。

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