Sellin B, Simonkovich E, Sellin E, Rey J L, Mouchet F
Med Trop (Mars). 1984 Oct-Dec;44(4):357-9.
In a dry savanna village in Upper-Volta, after mass treatment with metrifonate (four doses of 7,5 mg/kg at three weeks intervals) checking of the population was carried out for the three following years. In children and adolescents, results show a progressive decline in the cure rate (69.0% one year after treatment, 38.1% three years after treatment) and in egg-output reduction (69.9% one year after treatment, 75.4% three years after treatment). In adults, these two parameters still remain high three years after treatment (90.0% for cure rate and 87.3% for egg-output reduction). The authors point out that in a dry savanna village with a sedentary population and a transmission limited to a small collection of water, chemotherapy even employed alone is an appreciable control method to relieve populations.
在上沃尔特一个干旱的热带稀树草原村庄，在用敌百虫进行群体治疗（每三周一次，共四剂，剂量为7.5毫克/千克）后，在接下来的三年里对人群进行了检查。在儿童和青少年中，结果显示治愈率（治疗一年后为69.0%，治疗三年后为38.1%）和虫卵排出减少率（治疗一年后为69.9%，治疗三年后为75.4%）呈逐渐下降趋势。在成年人中，治疗三年后这两个参数仍然很高（治愈率为90.0%，虫卵排出减少率为87.3%）。作者指出，在一个人口定居、传播局限于一小片水源的干旱热带稀树草原村庄，即使单独使用化疗也是一种减轻人群痛苦的可观控制方法。
