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[异相睡眠的剥夺是否会干扰记忆痕迹的巩固?]

[Does deprivation of paradoxical sleep interfere with consolidation of memory traces?].

作者信息

Oniani T N

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1984 Nov-Dec;34(6):1086-92.

PMID:6543073
Abstract

The effect of paradoxical sleep deprivation (PSD) with water tank method on memory in the passive avoidance test as well as on open field behaviour was studied in rats. The effect of combining water tank PSD with a period of normal sleep-wakefulness cycle or with PSD non-emotional awakening was investigated in a special series of experiments. It is concluded that PSD, even by the water tank procedure, does not disturb trace consolidation and formation of long-term memory in the passive avoidance test. However, change in the correlation of motor-exploratory activity and fear reaction due to stress situation intrinsic in the water tank PSD procedure, does not allow the animals to reach comparatively long temporal criteria in the passive avoidance test.

摘要

采用水槽法进行异相睡眠剥夺(PSD)对大鼠被动回避试验中的记忆以及旷场行为的影响进行了研究。在一系列特殊实验中,研究了将水槽PSD与一段正常睡眠-觉醒周期或PSD非情绪唤醒相结合的效果。得出的结论是,即使通过水槽程序进行PSD,也不会干扰被动回避试验中的痕迹巩固和长期记忆的形成。然而,由于水槽PSD程序中固有的应激情况导致运动探索活动与恐惧反应的相关性发生变化,使得动物在被动回避试验中无法达到相对较长的时间标准。

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