Després J P, Bouchard C
Acta Genet Med Gemellol (Roma). 1984;33(3):475-80. doi: 10.1017/s0001566000005924.
Six skinfold measurements, and percent body fat and fat-free weight derived from the underwater weighing technique were obtained in 43 pairs of male and 44 pairs of female monozygotic (MZ) twins. A fat tissue biopsy was performed in the suprailiac region in 20 male and 16 female pairs in order to determine mean adipocyte diameter and basal lipolysis as well as epinephrine maximally stimulated lipolysis (10(-4) M). Twin resemblance in body fatness is clearly demonstrated by the analysis of the between MZ sibships over the within MZ shibship means of squares for all skinfold measurements, percent body fat and fat free weight (P less than 0.01). Within MZ pair similarity is as high in female as in male pairs for body fatness. Moreover, members of the same twin pair resemble one another significantly for fat cell size and fat cell lipolytic activities, particularly when epinephrine stimulated. In female MZ pairs, additional studies with control over the menstrual cycle are needed to clarify the case of isolated fat cell basal lipolysis.
对43对男性同卵双胞胎和44对女性同卵双胞胎进行了六项皮褶测量,并通过水下称重技术得出了体脂百分比和去脂体重。对20对男性和16对女性双胞胎的髂嵴上区域进行了脂肪组织活检,以确定平均脂肪细胞直径、基础脂肪分解以及肾上腺素最大刺激脂肪分解(10(-4)M)。通过对所有皮褶测量、体脂百分比和去脂体重的同卵双胞胎同胞间均值平方与同卵双胞胎同胞内均值平方进行分析,清楚地证明了同卵双胞胎在身体肥胖程度上的相似性(P<0.01)。在身体肥胖程度方面,同卵双胞胎女性对与男性对的相似程度一样高。此外,同一对双胞胎的成员在脂肪细胞大小和脂肪细胞脂肪分解活性方面彼此非常相似,尤其是在肾上腺素刺激时。在女性同卵双胞胎对中,需要进一步控制月经周期进行研究,以阐明孤立脂肪细胞基础脂肪分解的情况。