• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

单卵双胞胎在肥胖和脂肪细胞脂解方面的相似性。

Monozygotic twin resemblance in fatness and fat cell lipolysis.

作者信息

Després J P, Bouchard C

出版信息

Acta Genet Med Gemellol (Roma). 1984;33(3):475-80. doi: 10.1017/s0001566000005924.

DOI:10.1017/s0001566000005924
PMID:6543280
Abstract

Six skinfold measurements, and percent body fat and fat-free weight derived from the underwater weighing technique were obtained in 43 pairs of male and 44 pairs of female monozygotic (MZ) twins. A fat tissue biopsy was performed in the suprailiac region in 20 male and 16 female pairs in order to determine mean adipocyte diameter and basal lipolysis as well as epinephrine maximally stimulated lipolysis (10(-4) M). Twin resemblance in body fatness is clearly demonstrated by the analysis of the between MZ sibships over the within MZ shibship means of squares for all skinfold measurements, percent body fat and fat free weight (P less than 0.01). Within MZ pair similarity is as high in female as in male pairs for body fatness. Moreover, members of the same twin pair resemble one another significantly for fat cell size and fat cell lipolytic activities, particularly when epinephrine stimulated. In female MZ pairs, additional studies with control over the menstrual cycle are needed to clarify the case of isolated fat cell basal lipolysis.

摘要

对43对男性同卵双胞胎和44对女性同卵双胞胎进行了六项皮褶测量,并通过水下称重技术得出了体脂百分比和去脂体重。对20对男性和16对女性双胞胎的髂嵴上区域进行了脂肪组织活检,以确定平均脂肪细胞直径、基础脂肪分解以及肾上腺素最大刺激脂肪分解(10(-4)M)。通过对所有皮褶测量、体脂百分比和去脂体重的同卵双胞胎同胞间均值平方与同卵双胞胎同胞内均值平方进行分析,清楚地证明了同卵双胞胎在身体肥胖程度上的相似性(P<0.01)。在身体肥胖程度方面,同卵双胞胎女性对与男性对的相似程度一样高。此外,同一对双胞胎的成员在脂肪细胞大小和脂肪细胞脂肪分解活性方面彼此非常相似,尤其是在肾上腺素刺激时。在女性同卵双胞胎对中,需要进一步控制月经周期进行研究,以阐明孤立脂肪细胞基础脂肪分解的情况。

相似文献

1
Monozygotic twin resemblance in fatness and fat cell lipolysis.单卵双胞胎在肥胖和脂肪细胞脂解方面的相似性。
Acta Genet Med Gemellol (Roma). 1984;33(3):475-80. doi: 10.1017/s0001566000005924.
2
Adaptive changes to training in adipose tissue lipolysis are genotype dependent.脂肪组织脂肪分解训练的适应性变化取决于基因型。
Int J Obes. 1984;8(1):87-95.
3
Heredity and changes in body composition and adipose tissue metabolism after short-term exercise-training.短期运动训练后身体成分和脂肪组织代谢的遗传因素及变化
Eur J Appl Physiol Occup Physiol. 1987;56(4):398-402. doi: 10.1007/BF00417766.
4
Adipose tissue lipolysis after long-term overfeeding in identical twins.同卵双胞胎长期过度喂养后的脂肪组织脂肪分解
Int J Obes Relat Metab Disord. 1992 Mar;16(3):219-25.
5
Genotype dependency of adaptation in adipose tissue metabolism after short-term overfeeding.短期过量进食后脂肪组织代谢适应的基因型依赖性
Am J Physiol. 1986 Apr;250(4 Pt 1):E480-5. doi: 10.1152/ajpendo.1986.250.4.E480.
6
Genotype-controlled changes in body composition and fat morphology following overfeeding in twins.双胞胎过度喂养后身体成分和脂肪形态的基因型控制变化。
Am J Clin Nutr. 1986 May;43(5):723-31. doi: 10.1093/ajcn/43.5.723.
7
The influence of zygosity and chorion type on fat distribution in young adult twins consequences for twin studies.同卵双生状态和绒毛膜类型对年轻成年双胞胎脂肪分布的影响:对双胞胎研究的启示
Twin Res. 2001 Oct;4(5):356-64. doi: 10.1375/1369052012524.
8
Sensitivity to overfeeding: the Quebec experiment with identical twins.对过度喂养的敏感性:魁北克同卵双胞胎实验
Prog Food Nutr Sci. 1988;12(1):45-72.
9
Fat distribution and adipose tissue metabolism in non-obese male black African and Caucasian subjects.
Int J Obes. 1986;10(6):503-10.
10
Overfeeding in identical twins: 5-year postoverfeeding results.同卵双胞胎过度喂养:过度喂养5年后的结果。
Metabolism. 1996 Aug;45(8):1042-50. doi: 10.1016/s0026-0495(96)90277-2.

引用本文的文献

1
Genome-wide association study of adipocyte lipolysis in the GENetics of adipocyte lipolysis (GENiAL) cohort.全基因组关联研究脂肪细胞脂解在脂肪细胞脂解的遗传学(GENiAL)队列。
Mol Metab. 2020 Apr;34:85-96. doi: 10.1016/j.molmet.2020.01.009. Epub 2020 Jan 25.
2
Adipocyte morphology and implications for metabolic derangements in acquired obesity.脂肪细胞形态及其对后天性肥胖中代谢紊乱的影响。
Int J Obes (Lond). 2014 Nov;38(11):1423-31. doi: 10.1038/ijo.2014.31. Epub 2014 Feb 19.