Lukomska B, Olszewski W L, Ziolkowska A, Engeset A
Scand J Gastroenterol. 1984 Nov;19(8):1069-74.
The mononuclear cell populations were characterized phenotypically and functionally in the splenic, mesenteric, portal, sinusoidal, and hepatic venous blood. We found higher concentrations of mononuclear cells in splenic than mesenteric and portal blood; splenic blood contained high numbers of cells with Fc, C3b receptors and surface immunoglobulin and OX8+ (cytotoxic/suppressor) cells. Liver sinusoidal blood was enriched, compared with inflowing portal blood, in cells with Fc, C3b receptors and surface immunoglobulin, OX+8 cells, and natural killer and killer cells. These findings indicate that the spleen may be the main source of migrating streams of cells to the liver and that cytotoxic subsets of these cells are retained in that organ.
对脾、肠系膜、门静脉、肝血窦和肝静脉血中的单核细胞群体进行了表型和功能特征分析。我们发现脾血中的单核细胞浓度高于肠系膜血和门静脉血；脾血中含有大量具有Fc、C3b受体、表面免疫球蛋白的细胞以及OX8 +（细胞毒性/抑制性）细胞。与流入的门静脉血相比，肝血窦血中富含具有Fc、C3b受体、表面免疫球蛋白的细胞、OX + 8细胞、自然杀伤细胞和杀伤细胞。这些发现表明，脾脏可能是细胞向肝脏迁移流的主要来源，并且这些细胞的细胞毒性亚群保留在该器官中。
