Binder P S
Cornea. 1984;3(3):178-82.
Infection of newborns and immunocompromised hosts with herpes simplex virus appears to be no more common than in the normal adult. However, the disease tends to be more difficult to treat in the newborn because of poor patient compliance, delay in the diagnosis, and the tendency for retinal disease to occur. The disease is more difficult to treat in the immunocompromised host because of the necessity for maintenance of immunosuppression. Initial treatment is usually the same as used for adults unless intraocular infection occurs. Early diagnosis and treatment in the newborn can prevent corneal opacification and amblyopia, whereas ocular disease in the immunocompromised host may be an insignificant problem compared with infection elsewhere in the host's body.
新生儿和免疫功能低下宿主感染单纯疱疹病毒的情况似乎并不比正常成年人更常见。然而，由于患者依从性差、诊断延迟以及视网膜疾病发生的倾向，新生儿的这种疾病往往更难治疗。由于需要维持免疫抑制，免疫功能低下宿主的这种疾病更难治疗。除非发生眼内感染，初始治疗通常与成人相同。新生儿的早期诊断和治疗可预防角膜混浊和弱视，而与宿主身体其他部位的感染相比，免疫功能低下宿主的眼部疾病可能是一个不太重要的问题。
