Jones C L
Hurley Medical Center, Flint, Michigan, USA.
Neonatal Netw. 1996 Dec;15(8):11-5.
Herpes simplex virus (HSV) infections in the neonate can be acquired during pregnancy and during and following the birth process. The most common mode of transmission is from exposure to the virus in the birth canal at the time of delivery. HSV is among the less common infections in neonates. This often leads to delay in diagnosis and treatment, increasing the risk of a poor or fatal outcome. Clinically, HSV infection often presents in preterm or term infants with signs and symptoms similar to those of bacterial sepsis. Their immature immune systems puts preterm infants at higher risk for serious disease. A positive maternal history of HSV is not needed to support diagnosis; typically the mother is asymptomatic. Primary maternal infection usually leads to more serious disease in the neonate. It is important that caregivers recognize the subtle signs and symptoms of HSV infection so early diagnosis and prompt treatment can be instituted.
新生儿单纯疱疹病毒（HSV）感染可在孕期以及分娩过程中及之后获得。最常见的传播方式是在分娩时暴露于产道中的病毒。HSV是新生儿中较不常见的感染之一。这常常导致诊断和治疗延迟，增加不良或致命结局的风险。临床上，HSV感染常出现在早产或足月婴儿中，其体征和症状与细菌性败血症相似。他们未成熟的免疫系统使早产儿患严重疾病的风险更高。支持诊断不需要母亲有HSV阳性病史；通常母亲无症状。母亲原发性感染通常会导致新生儿患更严重的疾病。护理人员认识到HSV感染的细微体征和症状很重要，这样才能尽早进行诊断和及时治疗。
