Werblin T P, Peiffer R L, Fryczkowski A
Cornea. 1984;3(3):197-204.
Myopic hydrogen keratophakia offers several potential advantages over existing forms of corneal refractive surgery. Because no tissue lathing is required, neither donor tissue nor complex lathing equipment is necessary. Theoretically, hydrogen lens implants with precisely determined and verifiable parameters can be obtained in limitless supply. The surgical effect can be either modified or reversed, if clinically indicated. In this preliminary report, myopic hydrogel implants, with powers between -5 diopters and -20 diopters, were placed in nonhuman primate corneas. Corneascopic analysis showed significant flattening in all instances, and about 70% of the anticipated correction was actually observed. Operative complications were infrequent and generally resulted from traumatic wound dehiscence. Myopic hydrogel keratophakia has tremendous clinical potential, but requires further experimental testing as to safety and efficacy.
与现有的角膜屈光手术形式相比，近视性氢角膜晶状体植入术具有几个潜在优势。由于无需组织切削，因此既不需要供体组织，也不需要复杂的切削设备。从理论上讲，可以获得参数精确确定且可验证的氢晶状体植入物，并且供应无限。如果有临床指征，手术效果可以改变或逆转。在这份初步报告中，将屈光度在-5至-20之间的近视水凝胶植入物植入非人灵长类动物角膜中。角膜镜分析显示在所有情况下角膜均明显变平，实际观察到的矫正效果约为预期的70%。手术并发症很少见，通常是由创伤性伤口裂开引起的。近视性水凝胶角膜晶状体植入术具有巨大的临床潜力，但在安全性和有效性方面需要进一步的实验测试。
