Fujiu T, Ogino M
J Biomed Mater Res. 1984 Sep;18(7):845-59. doi: 10.1002/jbm.820180714.
Three types of surface active glasses and sintered apatite were implanted in femurs of rabbits for 8 and 16 weeks and subjected to the push-out test to measure the bone bonding strength. The apatite surface layers of these materials, which were formed under in vitro treatment, were studied using IR, NMR, and AES. The difference in the bonding strength among these materials was shown statistically. The results of in vitro experiments explained the differences. It was concluded that the crystal chemistry and formation rate of the surface apatite layer significantly influenced the bonding strength. Materials that formed a surface apatite layer having a bone-like crystal chemistry and fast formation rate showed high bone bonding strength.