Bharadwaj V K, Walling K E, Rees J, Novotny G M
J Otolaryngol. 1984 Oct;13(5):299-304.
Unilateral ulceration, bone necrosis, and sequestrum formation in the external auditory meatus are at times confused with the general diagnosis of keratosis obturans. However, the clinical presentation and the radiological and pathological characteristics of this condition are quite distinct from the latter. Initial examination in this situation may raise the suspicion of malignancy. When a true cholesteatoma of the external auditory meatus is found in association with this entity, according to a review of the available literature and personal observation of the authors, it is the result rather than the cause of this pathological process. In order to clarify this relationship, three patients are presented in whom there is radiological and histological evidence of bone necrosis and sequestration of a segment of the temporal bone but no evidence of hyperkeratosis in the ear canal.
外耳道的单侧溃疡、骨坏死和死骨形成有时会与闭塞性角化病的一般诊断相混淆。然而，这种情况的临床表现、放射学和病理学特征与后者截然不同。这种情况下的初步检查可能会引发对恶性肿瘤的怀疑。根据现有文献综述和作者的个人观察，当在外耳道发现真正的胆脂瘤与这种情况相关时，它是这种病理过程的结果而非原因。为了阐明这种关系，本文介绍了三名患者，他们有颞骨部分骨坏死和死骨形成的放射学和组织学证据，但耳道内没有角化过度的证据。
