耳毒性与噪声-药物相互作用
Ototoxicity and noise-drug interaction.
作者信息
Bhattacharyya T K, Dayal V S
出版信息
J Otolaryngol. 1984 Dec;13(6):361-6.
PMID:6544852
Abstract
Diverse therapeutic agents, such as certain antibiotics, diuretics, and analgesics can cause functional and morphological damage to the inner ear. Noise present in recreational or occupational environment may also be potentially damaging to the auditory system when combined with some ototoxic therapeutic agents. This article documents recent research and controversies about the site and mechanism of action of major ototoxic drugs, noise-drug interaction, and possible prophylaxis against such ototoxicity.
摘要
多种治疗药物，如某些抗生素、利尿剂和镇痛药，可对内耳造成功能和形态损伤。娱乐或职业环境中的噪音与某些耳毒性治疗药物合用时，也可能对听觉系统有潜在损害。本文记录了关于主要耳毒性药物的作用部位和作用机制、噪声与药物相互作用以及针对此类耳毒性可能的预防措施的最新研究和争议。
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