Viswanathan M, George J C
J Pineal Res. 1984;1(1):69-74. doi: 10.1111/j.1600-079x.1984.tb00196.x.
The role of the pineal gland in diet-induced thermogenesis (DIT) and growth of brown adipose tissue (BAT) in rats during voluntary overfeeding was studied using pinealectomized and sham-pinealectomized rats. Overfeeding was induced by offering the animals a cafeteria-diet (CD) which contained a selection of highly palatable food items. Rats which were fed CD had significantly increased interscapular brown adipose tissue (IBAT) mass and increased tail-skin temperature indicating the importance of the tail in thermoregulation during DIT. Pinealectomy had no effect on the increase in tail-skin temperature and deposition of IBAT, which were stimulated by CD feeding. These findings suggest that the pineal is not directly involved in modulating the metabolism of BAT in rats.
利用松果体切除和假松果体切除的大鼠，研究了松果体在大鼠自愿过度喂养期间饮食诱导产热（DIT）和棕色脂肪组织（BAT）生长中的作用。通过给动物提供包含多种高度可口食物的自助饮食（CD）来诱导过度喂养。喂食CD的大鼠肩胛间棕色脂肪组织（IBAT）质量显著增加，尾皮温度升高，表明尾巴在DIT期间体温调节中的重要性。松果体切除对CD喂养刺激引起的尾皮温度升高和IBAT沉积没有影响。这些发现表明，松果体不直接参与调节大鼠BAT的代谢。
