Cooper P H, Frierson H F
Arch Pathol Lab Med. 1984 Jan;108(1):55-7.
An example of papillary eccrine adenoma was seen. This benign cutaneous tumor has a diagnostic microscopic appearance that consists of multiple ducts lined by two or more layers of cells. The inner layer often forms one or multiple papillae of variable complexity. The stroma consists of patches of loosely arranged spindled cells and areas of hyalinized collagen. The latter often forms bands about the ducts. In addition to the foregoing, we observed focal squamous differentiation, clear cell change, connection of ducts to the epidermis, and prominent nerves within the stroma. Papillary eccrine adenoma also has several characteristic clinical features. The tumors are firm or hard nodules, frequently of many years' duration, and a large proportion are situated on the extremities of black persons.
可见一例乳头状小汗腺腺瘤。这种良性皮肤肿瘤具有诊断性的微观表现，由两层或更多层细胞衬里的多个导管组成。内层常形成一个或多个复杂程度不一的乳头。间质由散在排列的梭形细胞片和玻璃样变的胶原区域组成。后者常围绕导管形成条索状。除此之外，我们还观察到局灶性鳞状分化、透明细胞改变、导管与表皮相连以及间质内有明显的神经。乳头状小汗腺腺瘤也有一些特征性的临床特点。肿瘤为坚实或坚硬的结节，病程常达数年，且很大一部分位于黑人的四肢。
