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绒毛膜血管病。新生儿发病和死亡的一个重要胎盘征象。

Chorangiosis. An important placental sign of neonatal morbidity and mortality.

作者信息

Altshuler G

出版信息

Arch Pathol Lab Med. 1984 Jan;108(1):71-4.

PMID:6546343
Abstract

Chorangiosis is a placental change that has not been studied, to my knowledge, by investigators who publish in English. It occurs rarely in normal pregnancies. Each year, however, more than 30,000 neonates in the United States die within the first 28 days of life. Of 1,350 singleton newborns hospitalized in a regional neonatal intensive care unit, 74 (5%) had chorangiosis. One hundred thirty-four informational items of clinical, placental, and autopsy data were evaluated with a computer program written in Microsoft Basic. Depending on the gestational age of the population studied and the severity of the chorangiosis, the incidences of neonatal death and major congenital malformations were as high as 39% and 42%, respectively. Detailed findings introduce question of etiologic association with gestational diabetes, toxemia of pregnancy, and placental infection.

摘要

据我所知,绒毛膜血管病是一种尚未被用英文发表研究成果的研究者所研究过的胎盘变化。它在正常妊娠中很少发生。然而,美国每年有超过30000名新生儿在出生后的头28天内死亡。在一个地区新生儿重症监护病房住院的1350名单胎新生儿中,74例(5%)患有绒毛膜血管病。利用用微软Basic语言编写的计算机程序对134项临床、胎盘和尸检数据信息进行了评估。根据所研究人群的胎龄和绒毛膜血管病的严重程度,新生儿死亡和主要先天性畸形的发生率分别高达39%和42%。详细的研究结果引发了与妊娠糖尿病、妊娠中毒症和胎盘感染之间病因学关联的问题。

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Chorangiosis. An important placental sign of neonatal morbidity and mortality.绒毛膜血管病。新生儿发病和死亡的一个重要胎盘征象。
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