人体内二乙酰吗啡代谢物的鉴定。
Identification of diacetylmorphine metabolites in humans.
作者信息
Yeh S Y, McQuinn R L, Gorodetzky C W
出版信息
J Pharm Sci. 1977 Feb;66(2):201-4. doi: 10.1002/jps.2600660217.
PMID:65466
Abstract
With the techniques of column chromatography, TLC, and GLC, morphine, 6-acetylmorphine, normorphine, morphine 3-glucuronide, 6-acetylmorphine 3-glucuronide, and normorphine glucuronide were identified as metabolites of diacetylmorphine (heroin) in the urine of humans administered 10 mg iv/70 kg body weight.
摘要
运用柱色谱法、薄层色谱法和气相色谱法等技术，在静脉注射10毫克/70千克体重二乙酰吗啡（海洛因）的人体尿液中，吗啡、6-乙酰吗啡、去甲吗啡、吗啡3-葡萄糖醛酸苷、6-乙酰吗啡3-葡萄糖醛酸苷和去甲吗啡葡萄糖醛酸苷被鉴定为二乙酰吗啡（海洛因）的代谢产物。
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