肾性糖尿患者的免疫学特征

Immunological characterization of renal glycosuria patients.

作者信息

De Paoli P, Battistin S, Jus A, Reitano M, Villalta D, De Marchi S, Cecchin E, Basile A, Santini G

出版信息

Clin Exp Immunol. 1984 May;56(2):289-94.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1536240/

Abstract

We have evaluated the autoantibody pattern, the production of specific immunoglobulins against bacteria in the urinary tract and lymphocytes populations in peripheral blood of primary renal glycosuria patients. All the affected members present autoantibodies against various antigens. In nine patients immunofluorescence revealed antibody coated bacteria in urine specimens. Imbalances in lymphocytes subpopulations are also present, with a reduction of OKT8+ cells and an increase of B and natural killer cells. These results support previous observations about immunological abnormalities in these patients.

摘要

我们评估了原发性肾性糖尿患者的自身抗体模式、针对泌尿道细菌的特异性免疫球蛋白产生情况以及外周血淋巴细胞群体。所有受影响成员均存在针对各种抗原的自身抗体。9例患者的尿液标本免疫荧光检查显示有抗体包被细菌。淋巴细胞亚群也存在失衡，OKT8 +细胞减少，B细胞和自然杀伤细胞增加。这些结果支持了先前关于这些患者免疫异常的观察结果。

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