André J, Arnaud B, Pilonchery G, Leriche A
Ann Biol Clin (Paris). 1980;38(2):111-4.
Antibody coating of urinary bacteria was performed in order to localize the site of recurrent urinary tract infections in 39 para or tetraplegics. The antibody-coated bacteria test was positive with anti human globulin in 19 out of 39 patients: upper urinary tract infections 7/10, prostatitis 3/3, lower urinary tract infections 9/26. Of the 19 patients with positive antibody-coated bacteria test 14 were tested with monospecific antisera: 13 were IgG positive and 11 were IgA positive; IgM was never present. Among the 11 IgA positive tests, we search for the presence of IgA secretory piece in 8 and all were positive. The immunoglobulins on the bacterial wall result, in part, from local production of urinary antibody. Although positive results with anti human globulins occurred frequently in patients with lower urinary tract infections, this test appears to be a useful screening test for localization of infection in patients with recurrent urinary tract infection.
为了确定39例截瘫或四肢瘫痪患者复发性尿路感染的部位，对尿细菌进行了抗体包被检测。在39例患者中，19例抗人球蛋白抗体包被细菌检测呈阳性：上尿路感染7/10，前列腺炎3/3，下尿路感染9/26。在19例抗体包被细菌检测呈阳性的患者中，14例用单特异性抗血清检测：13例IgG阳性，11例IgA阳性；从未检测到IgM。在11例IgA阳性检测中，我们对其中8例检测了IgA分泌片的存在，结果均为阳性。细菌壁上的免疫球蛋白部分源于尿抗体的局部产生。虽然抗人球蛋白检测阳性结果在复发性下尿路感染患者中经常出现，但该检测似乎是复发性尿路感染患者感染部位定位的一种有用的筛查检测。
