Godel J C, Hart A G
Can Med Assoc J. 1984 Aug 1;131(3):199-204.
A syndrome is described that affected 16 Indian and Inuit infants roughly 3 months old, most of whom were born in settlements in the Canadian Arctic. The infants presented with a clinical picture that included hepatitis, hemolytic anemia, rickets and respiratory distress, a combination that resembled a syndrome first described in malnourished infants at the turn of the century by von Jaksch and Luzet. The clinical course was self-limited, and all the infants survived without sequelae. The cause of the syndrome was not determined; no infectious agents were discovered. However, low levels of vitamins A, C, D and E were found in a few infants in whom assays were done. The implications of these findings and their relation to the possible cause of this "northern infant syndrome" are discussed.
描述了一种综合征，该综合征影响了约16名3个月大的印度和因纽特婴儿，其中大多数出生在加拿大北极地区的定居点。这些婴儿呈现出包括肝炎、溶血性贫血、佝偻病和呼吸窘迫在内的临床症状，这一症状组合类似于世纪之交由冯·雅克施和吕泽特首次描述的营养不良婴儿的一种综合征。临床病程为自限性，所有婴儿均存活且无后遗症。该综合征的病因尚未确定；未发现感染因子。然而，在少数进行检测的婴儿中发现维生素A、C、D和E水平较低。讨论了这些发现的意义及其与这种“北方婴儿综合征”可能病因的关系。
