Wolfe D W, Scopelliti J A, Boselli B D
Cancer. 1984 Sep 15;54(6):1085-7. doi: 10.1002/1097-0142(19840915)54:6<1085::aid-cncr2820540626>3.0.co;2-s.
Central nervous system involvement has not previously been described in patients with hairy cell leukemia (HCL). A patient is reported who presented with meningeal involvement as his initial symptom of HCL. Diagnosis was established by morphologic and cytochemical studies of his cerebrospinal fluid (CSF) and bone marrow. Treatment with whole-brain irradiation and intrathecal chemotherapy was successful in clearing leukemic cells from the CSF with resolution of symptoms.
中枢神经系统受累此前在毛细胞白血病（HCL）患者中尚未有过描述。本文报告了一名以脑膜受累作为HCL首发症状的患者。通过对其脑脊液（CSF）和骨髓进行形态学及细胞化学研究确诊。全脑照射和鞘内化疗成功清除了CSF中的白血病细胞，症状得以缓解。
