Greer F R, Lane J, Ho M
Am J Clin Nutr. 1984 Sep;40(3):562-8. doi: 10.1093/ajcn/40.3.562.
The roles of vitamin D, calcitonin, and parathyroid hormone in calcium metabolism during lactation may be more evident in women secreting very large amounts of milk for a number of months, as in mothers nursing twins. We report significant increases in serum concentrations of parathyroid hormone, calcitonin, and 1,25(OH)2 vitamin D in mothers nursing twins compared to mothers nursing single infants. Serum concentrations of calcium actually increased in both groups during lactation. Maternal intakes of calories, calcium, and phosphorus were significantly higher in mothers nursing twins. Thus, mothers nursing twins were able to compensate for higher calcium losses in breast milk by increased dietary intakes of calcium as well as increased serum concentrations of parathyroid hormone, calcitonin, and 1,25(OH)2 vitamin D.
在哺乳期，维生素D、降钙素和甲状旁腺激素在钙代谢中的作用，在那些连续数月分泌大量乳汁的女性中可能更为明显，比如哺乳双胞胎的母亲。我们报告称，与哺乳单胎婴儿的母亲相比，哺乳双胞胎的母亲血清中甲状旁腺激素、降钙素和1,25(OH)₂维生素D的浓度显著升高。哺乳期两组母亲的血清钙浓度实际上都有所增加。哺乳双胞胎的母亲热量、钙和磷的母体摄入量显著更高。因此，哺乳双胞胎的母亲能够通过增加饮食中钙的摄入量以及血清中甲状旁腺激素、降钙素和1,25(OH)₂维生素D的浓度升高，来补偿母乳中更高的钙损失。
