与鞘内注射二醋吗啡联合使用的止吐药的评估。
Evaluation of anti-emetics in association with intrathecal diamorphine.
作者信息
Barron D W
出版信息
Ann R Coll Surg Engl. 1984 Sep;66(5):359-60.
Abstract
Intrathecal diamorphine is associated with a high incidence of emetic symptoms. Six anti-emetic drugs representing various chemical groups were given in random order to patients undergoing total hip replacement and who had received intrathecal diamorphine 0.5-1.0 mg. The phenothiazines, perphenazine and prochlorperazine, were more effective than the others. It is suggested that this might be a useful model for the evaluation of new anti-emetics.
摘要
鞘内注射二醋吗啡会出现高发生率的呕吐症状。六种代表不同化学类别的止吐药物被随机给予接受全髋关节置换术且已接受0.5 - 1.0毫克鞘内注射二醋吗啡的患者。吩噻嗪类药物奋乃静和丙氯拉嗪比其他药物更有效。有人认为这可能是评估新型止吐药的一个有用模型。
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