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New antitumor antibiotic, LL-C10037 alpha. Fermentation, isolation and structure determination.

作者信息

Lee M D, Fantini A A, Morton G O, James J C, Borders D B, Testa R T

出版信息

J Antibiot (Tokyo). 1984 Oct;37(10):1149-52. doi: 10.7164/antibiotics.37.1149.

DOI:10.7164/antibiotics.37.1149
PMID:6548735
Abstract

A new antitumor antibiotic, LL-C10037 alpha was isolated from the fermentation filtrate of a Streptomyces by adsorption, partition and reverse phase column chromatography. Its chemical structure was determined by 1H NMR, 13C NMR, UV, IR and mass spectral data. LL-C10037 alpha is a gamma-aminoepoxysemiquinone and is related to the epoxyguinone class of antibiotics.

摘要

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