Novel antitumor antibiotic phospholine. 1. Production, isolation and characterization.
作者信息
Ozasa T, Suzuki K, Sasamata M, Tanaka K, Kobori M, Kadota S, Nagai K, Saito T, Watanabe S, Iwanami M
机构信息
Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd., Tokyo, Japan.
出版信息
J Antibiot (Tokyo). 1989 Sep;42(9):1331-8. doi: 10.7164/antibiotics.42.1331.
PMID:2793586
Abstract
Phospholine was isolated as an antitumor antibiotic from the fermentation broth of Streptomyces hygroscopicus. Phospholine is an amphoteric compound which has an amino group and a phosphoric acid ester as functional groups. Phospholine shows strong activities against L1210, P388 and EL-4.
摘要
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