Sussi P L, Burro A, Plebani M, Abrescia F, Perazzolo E, Petronio R
Chir Ital. 1984 Aug;36(4):643-7.
The Authors report the behaviour of antithyroid and antimicrosomial antibodies in a group of 394 patients suffering from nodular struma, thyroid adenoma and carcinoma, Hashimoto's thyroiditis, other thyroidites and Basedow's disease. The autoimmune pathology (Hashimoto's thyroiditis and Basedow's disease) is joined to a higher frequency of positive titles for both antibodies. In such pathology we also meet the highest titles. In the non-autoimmune pathology the antimicrosomial antibodies are more frequently positive than the antithyroid ones. If one considers the behaviour of both antibodies, the specificness about the diagnosis of thyroiditis increases.
作者报告了394例患有结节性甲状腺肿、甲状腺腺瘤和癌、桥本甲状腺炎、其他甲状腺炎以及突眼性甲状腺肿的患者体内抗甲状腺抗体和抗微粒体抗体的表现。自身免疫性病理(桥本甲状腺炎和突眼性甲状腺肿)与两种抗体阳性率较高相关。在这种病理情况下,我们也发现了最高的抗体滴度。在非自身免疫性病理中,抗微粒体抗体比抗甲状腺抗体更频繁地呈阳性。如果考虑两种抗体的表现,甲状腺炎诊断的特异性会增加。