Axelsson C K, Szecsi P B, Nielsen M D
Scand J Gastroenterol. 1984 Nov;19(8):1114-8.
The concentration of group I pepsinogens (PG I) in serum was determined in 235 healthy persons and hospital controls. The concentration was significantly higher in males. Correction of PG I with regard to body weight or lean body mass eliminated the sex difference but not the weak correlation with age. The normal range was 0.60-3.3 ng PG I/ml serum/kg body weight. For comparison with other PG I studies another normal range, 46-211 ng PG I/ml serum, was calculated as the 95% interpercentile range of the present PG I concentrations. In a study of diurnal rhythm and in a 6-month study of seasonal variation, no significant variation of PG I in serum was found. Serious non-gastric surgical disease did not influence the PG I level in serum. The PG I levels in blood groups O, A, and B did not differ significantly.
对235名健康人和医院对照者测定了血清中I组胃蛋白酶原（PG I）的浓度。男性的浓度显著更高。根据体重或去脂体重校正PG I后消除了性别差异，但与年龄的弱相关性并未消除。正常范围为0.60 - 3.3 ng PG I/毫升血清/千克体重。为了与其他PG I研究进行比较，计算出另一个正常范围，即46 - 211 ng PG I/毫升血清，作为当前PG I浓度的95%百分位数范围。在一项昼夜节律研究和一项为期6个月的季节变化研究中，未发现血清中PG I有显著变化。严重的非胃部外科疾病并未影响血清中的PG I水平。O、A和B血型的PG I水平无显著差异。
