Worthington-Roberts B, Weigle A
JOGN Nurs. 1983 Jan-Feb;12(1):21-4. doi: 10.1111/j.1552-6909.1983.tb01047.x.
Caffeine is a drug which easily crosses the placental barrier and enters the fetal circulation. To date, most studies that demonstrate caffeine's teratogenic potential have been conducted in animal models. Although no definite relationship in humans has been confirmed, it is suggested that a pregnant woman should limit or discontinue her intake of caffeine.
咖啡因是一种能轻易穿过胎盘屏障并进入胎儿循环的药物。迄今为止,大多数证明咖啡因具有致畸潜力的研究都是在动物模型中进行的。尽管尚未证实人类之间存在明确的关联,但建议孕妇限制或停止摄入咖啡因。