Kalbfleisch J H, Stowe D F, Smith J J
Am Heart J. 1978 Jun;95(6):707-15. doi: 10.1016/0002-8703(78)90500-8.
A study has been made of the heart rate (HR) response to the Valsalva maneuver in five different groups of normal white males and two groups of male coronary heart disease (CHD) patients using non-invasive methods. By means of the analysis of variance the effects of age, posture, Valsalva phase and CHD on the HR response were assessed. Both age and CHD were factors that reduce the HR response. Further analysis indicated that the HR change from Phase 3 to Phase 4 in the Valsalva was the preferred discriminator between normals and cardiac patients. We have derived a "Valsalva score" that can be used to identify HR changes that deviate from the expected average normal response for a given age, control HR and Phase 3 HR. HR assessment of the Valsalva maneuver is a simple safe non-invasive test. An abnormal response suggests altered functioning of hemodynamic or autonomic cardiovascular mechanisms governing HR control.
采用非侵入性方法,对五组正常白人男性和两组男性冠心病(CHD)患者进行了Valsalva动作心率(HR)反应的研究。通过方差分析评估了年龄、姿势、Valsalva动作阶段和冠心病对HR反应的影响。年龄和冠心病都是降低HR反应的因素。进一步分析表明,Valsalva动作中从第3阶段到第4阶段的HR变化是区分正常人和心脏病患者的首选指标。我们得出了一个“Valsalva评分”,可用于识别与给定年龄、对照心率和第3阶段心率的预期平均正常反应不同的HR变化。Valsalva动作的HR评估是一种简单、安全的非侵入性测试。异常反应表明控制HR的血流动力学或自主心血管机制功能改变。