高剂量口服激肽释放酶治疗特发性男性不育症的效果：通过无透明带仓鼠卵体外穿透试验进行评估。
Effect of high dose oral Kallikrein treatment in men with idiopathic subfertility: evaluation by means of in vitro penetration test of zona free hamster ova.
作者信息
Comhaire F, Vermeulen L
出版信息
Int J Androl. 1983 Apr;6(2):168-72. doi: 10.1111/j.1365-2605.1983.tb00335.x.
Abstract
High dose oral Kallikrein treatment (600 U Padutine per day) was given to 10 infertile men with poor semen quality. After 3 months of this treatment no pregnancies occurred, and no significant changes in routine semen characteristics were observed. Moreover, the capacity of the spermatozoa to migrate in vitro and to penetrate zona free hamster ova remained unchanged after Kallikrein ingestion. It is concluded that Kallikrein treatment was ineffective in these men.
摘要
对10名精液质量差的不育男性给予大剂量口服激肽释放酶治疗（每天600单位Padutine）。经过3个月的这种治疗，没有发生妊娠，并且未观察到常规精液特征有显著变化。此外，摄入激肽释放酶后，精子在体外迁移和穿透去透明带仓鼠卵的能力保持不变。得出的结论是，激肽释放酶治疗对这些男性无效。
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