细胞密度对细胞表面免疫球蛋白消失的影响。
Effect of cell density on the disappearance of cell surface immunoglobulins.
作者信息
Moraru I, Gherman M, Sulica A, Bancu A C, Sjöquist J, Ghetie V
出版信息
Ann Immunol (Paris). 1978 Jan;129(1):89-96.
PMID:655649
Abstract
Mouse macrophages and human peripheral blood lymphocytes exhibiting on the membrane autologous IgG as well as mouse thymocytes coated with human IgG, showed a strong cell concentration dependence of surface IgG disappearance during an incubation at 37 degrees C. Mouse spleen lymphocytes treated with anti-mouse Ig behaved in the same way regarding the disappearance of surface immunoglobulins, while the redistribution of ligands (cap formation) was not dependent on cell concentration.
摘要
在细胞膜上呈现自体IgG的小鼠巨噬细胞和人外周血淋巴细胞，以及包被有人IgG的小鼠胸腺细胞，在37℃孵育期间表面IgG的消失表现出强烈的细胞浓度依赖性。用抗小鼠Ig处理的小鼠脾淋巴细胞在表面免疫球蛋白消失方面表现相同，而配体的重新分布（帽形成）则不依赖于细胞浓度。
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