肿瘤结合免疫球蛋白。包被肿瘤细胞表面免疫球蛋白的体外消失及释放成分的一些特性。
Tumour-bound immunoglobulins. The in vitro disappearance of immunoglobulin from the surface of coated tumour cells, and some properties of released components.
作者信息
Ran M, Fish F, Witz I P, Klein G
出版信息
Clin Exp Immunol. 1974 Mar;16(3):335-53.
Abstract
Immunoglobulin-coated ascites tumour cells lose some of their immunoglobulin coat following their transfer to culture conditions. The uncoating process is metabolism-dependent and related to the turning over of cell-surface components. Uncoated tumour cells bind globulin isolated from tumour eluates more efficiently than coated cells. Analysis of the spent medium of short-term tumour cell cultures revealed the presence of both immunoglobulin and antigenic cell surface components.
摘要
免疫球蛋白包被的腹水肿瘤细胞在转移至培养条件后会失去部分免疫球蛋白包被。脱包被过程依赖于代谢，且与细胞表面成分的更新有关。未包被的肿瘤细胞比包被的细胞更有效地结合从肿瘤洗脱液中分离出的球蛋白。对短期肿瘤细胞培养的用过的培养基进行分析发现存在免疫球蛋白和抗原性细胞表面成分。
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引用本文的文献
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Tumour-bound immunoglobulins. The fate of immunoglobulin disappearing from the surface of coated tumour cells.肿瘤结合免疫球蛋白。从包被肿瘤细胞表面消失的免疫球蛋白的命运。
Clin Exp Immunol. 1974 Mar;16(3):355-65.
2
Tumour-bound immunoglobulins. The in vitro fixation of radioiodine-labelled anti-immunoglobulin reagents by tumour cells.肿瘤结合免疫球蛋白。肿瘤细胞对放射性碘标记的抗免疫球蛋白试剂的体外固定作用。
Clin Exp Immunol. 1974 Mar;16(3):321-33.
本文引用的文献
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Histocompatibility changes in tumors.肿瘤中的组织相容性变化。
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Suggestive evidence that the "blocking antibodies" of tumor-bearing individuals may be antigen--antibody complexes.有提示性证据表明，荷瘤个体的“封闭抗体”可能是抗原-抗体复合物。
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Spontaneous release of cytotoxic alloantibody from viable cells sensitized in excess antibody.在过量抗体中致敏的活细胞自发释放细胞毒性同种抗体。
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5
Tumour-bound immunoglobulins. The fate of immunoglobulin disappearing from the surface of coated tumour cells.肿瘤结合免疫球蛋白。从包被肿瘤细胞表面消失的免疫球蛋白的命运。
Clin Exp Immunol. 1974 Mar;16(3):355-65.
6
Tumour-bound immunoglobulins. The in vitro fixation of radioiodine-labelled anti-immunoglobulin reagents by tumour cells.肿瘤结合免疫球蛋白。肿瘤细胞对放射性碘标记的抗免疫球蛋白试剂的体外固定作用。
Clin Exp Immunol. 1974 Mar;16(3):321-33.
7
Blocking of lymphocyte-mediated cytotoxicity for rat hepatoma cells by tumour-specific antigen-antibody complexes.肿瘤特异性抗原-抗体复合物对大鼠肝癌细胞淋巴细胞介导细胞毒性的阻断作用。
Nat New Biol. 1972 Aug 9;238(84):185-6. doi: 10.1038/newbio238185a0.
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Prog Allergy. 1969;13:174-272.
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Transplant Proc. 1970 Mar;2(1):68-75.
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