Berkel A I, Ersoy F
Boll Ist Sieroter Milan. 1978 Mar 31;57(1):26-9.
In the recent studies conducted in patients with various types of primary immunodeficiency diseases, an increased frequency of HLA-A1 or HLA-A2 antigens was reported. In order to determine the frequency of the histocompatibility antigens in ataxia telangiectasia (A-T), HLA typing was carried out in 30 patients with A-T along with their 23 parents and 4 siblings. The results were compared with 138 healthy controls. That study showed no significant difference for the frequencies of 19 HLA antigens of the A and B loci between the controls and A-T patients or their parents-siblings.
在近期针对各类原发性免疫缺陷病患者开展的研究中，有报告称HLA - A1或HLA - A2抗原的出现频率有所增加。为了确定共济失调毛细血管扩张症（A - T）中组织相容性抗原的频率，对30例A - T患者及其23名父母和4名兄弟姐妹进行了HLA分型。将结果与138名健康对照者进行了比较。该研究表明，对照组与A - T患者或其父母 - 兄弟姐妹之间，A和B位点的19种HLA抗原频率没有显著差异。
