标准化应激与高血压：普萘洛尔和甲基多巴疗效比较
Standardized stress and hypertension: comparison of effect of propranolol and methyldopa.
作者信息
Dunn F G, Melville D I, Jones J V, Lorimer A R, Lawrie T D
出版信息
Br J Clin Pharmacol. 1978 Mar;5(3):223-6. doi: 10.1111/j.1365-2125.1978.tb01628.x.
Abstract
1 Using a standardized form of mental stress, 21 patients with idiopathic hypertension were investigated before and after treatment with placebo (n=8), propranolol (n=7) or methyldopa (n=6). 2 Blood pressure was satisfactorily controlled in the propranolol and methyldopa groups but only the propranolol group showed modification of the pressor response to stress testing. 3 These results suggest that propranolol may provide more uniform control of blood pressure than methyldopa in patients with essential hypertension.
摘要
- 使用标准化的精神应激形式，对21例特发性高血压患者在接受安慰剂（n = 8）、普萘洛尔（n = 7）或甲基多巴（n = 6）治疗前后进行了研究。2. 普萘洛尔组和甲基多巴组的血压得到了满意控制，但只有普萘洛尔组对应激测试的升压反应有所改变。3. 这些结果表明，在原发性高血压患者中，普萘洛尔对血压的控制可能比甲基多巴更稳定。
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Standardized stress and hypertension: comparison of effect of propranolol and methyldopa.标准化应激与高血压：普萘洛尔和甲基多巴疗效比较
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