Suppr超能文献

雪貂孕期流感感染与胎儿流失的关联。

Association of foetal wastage with influenza infection during ferret pregnancy.

作者信息

Collie M H, Sweet C, Cavanagh D, Smith H

出版信息

Br J Exp Pathol. 1978 Apr;59(2):190-5.

Abstract

Inoculation of influenza virus into pregnant ferrets during the late gestational period was investigated. Foetal resorption followed intracardial inoculation of a large dose of influenza virus (10(9.4) EBID50) and a 100-fold lower dose caused lower litter sizes at birth. The possible role of fever in foetal resorptions was largely discounted by 2 observations: a non-pyrexic dose inoculated intracardially into the pregnant ferret still had detrimental effects on foetal viability; influenza virus inoculated intranasally caused a pyrexia but did not affect the progeny. The potential of the ferret as a model for studying the possible adverse effects of influenza during pregnancy is discussed.

摘要

研究了在妊娠后期将流感病毒接种到怀孕雪貂体内的情况。在心脏内接种大剂量流感病毒(10(9.4) EBID50)后出现胎儿吸收,而剂量降低100倍则导致出生时窝仔数减少。两项观察结果很大程度上排除了发热在胎儿吸收中的可能作用:经心脏内接种到怀孕雪貂体内的无热剂量仍对胎儿活力有不利影响;经鼻接种流感病毒会引起发热,但不影响后代。讨论了雪貂作为研究孕期流感可能产生的不良影响的模型的潜力。

相似文献

4
The influence of influenza infection on praenatal development of mice.
Acta Univ Carol Med (Praha). 1978;24(1-2):43-55.

引用本文的文献

1
Maternal Influenza and Offspring Neurodevelopment.母亲流感与子代神经发育
Curr Issues Mol Biol. 2024 Jan 2;46(1):355-366. doi: 10.3390/cimb46010023.
6
Influenza pathogenicity during pregnancy in women and animal models.孕期女性及动物模型中的流感致病性。
Semin Immunopathol. 2016 Nov;38(6):719-726. doi: 10.1007/s00281-016-0580-2. Epub 2016 Jul 7.
10
Pathogenicity of influenza virus.流感病毒的致病性。
Microbiol Rev. 1980 Jun;44(2):303-30. doi: 10.1128/mr.44.2.303-330.1980.

本文引用的文献

1
Asian influenza during pregnancy and congenital malformations.孕期感染亚洲流感与先天性畸形
Acta Pathol Microbiol Scand. 1960;49:114-26. doi: 10.1111/j.1699-0463.1960.tb01121.x.
5
Virological studies on experimental infection of pregnant mice with influenza virus.
Tohoku J Exp Med. 1966 Aug 25;89(4):321-40. doi: 10.1620/tjem.89.321.
9
Influenza, hyperthermia, and congenital malformation.流感、高热与先天性畸形。
Lancet. 1972 Feb 5;1(7745):320-1. doi: 10.1016/s0140-6736(72)90327-3.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验