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1
Long-term hypotensive effect of atenolol 4% eyedrops.4%阿替洛尔滴眼液的长期降压作用。
Br J Ophthalmol. 1978 May;62(5):287-91. doi: 10.1136/bjo.62.5.287.
2
Atenolol versus adrenaline eye drops and an evaluation of these two combined.阿替洛尔与肾上腺素滴眼液以及两者联合使用的评估。
Br J Ophthalmol. 1978 May;62(5):296-301. doi: 10.1136/bjo.62.5.296.
3
[Atenolol: its effects on pressure in open-angle glaucoma].
J Fr Ophtalmol. 1978 Mar;1(3):205-9.
4
Atenolol 4% eyedrops in glaucoma simplex.
Doc Ophthalmol. 1980 Apr 15;48(2):309-14. doi: 10.1007/BF00141458.
5
Comparison of ocular hypotensive effects of acetazolamide and atenolol.乙酰唑胺和阿替洛尔的降眼压效果比较。
Br J Ophthalmol. 1977 May;61(5):345-8. doi: 10.1136/bjo.61.5.345.
6
Atenolol 4% eye drops and glaucoma. A double-blind short-term clinical trial of a new beta1-adrenergic blocking agent.
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1977 Dec 31;205(1):61-70. doi: 10.1007/BF00413464.
7
[Long-term treatment of open-angle glaucoma with bupranolol eye drops (author's transl)].
Klin Monbl Augenheilkd. 1980 Oct;177(4):523-6. doi: 10.1055/s-2008-1057682.
8
[Adrenaline eye drops in the treatment of glaucoma].
Klin Monbl Augenheilkd. 1968 Mar;152(3):398-404.
9
Ocular hypotensive effect of atenolol (Tenormin, I.C.I.). A new beta-adrenergic blocker.阿替洛尔（氨酰心安，帝国化学工业公司产品）的降眼压作用。一种新型β-肾上腺素能阻滞剂。
Br J Ophthalmol. 1975 Jun;59(6):296-300. doi: 10.1136/bjo.59.6.296.
10
Atenolol eye drops in glaucoma: a double-masked, controlled study.阿替洛尔滴眼液治疗青光眼：一项双盲对照研究。
Br J Ophthalmol. 1977 May;61(5):349-53. doi: 10.1136/bjo.61.5.349.

引用本文的文献

1
Atenolol 4% eyedrops in glaucoma simplex.
Doc Ophthalmol. 1980 Apr 15;48(2):309-14. doi: 10.1007/BF00141458.
2
A dose-response study of oral atenolol administered once daily in patients with raised intra-ocular pressure.
Graefes Arch Clin Exp Ophthalmol. 1982;218(2):96-8. doi: 10.1007/BF02153719.
3
Comparison of ocular hypotensive effects of 3 dosages of oral atenolol.三种剂量口服阿替洛尔的降眼压效果比较。
Br J Ophthalmol. 1983 Oct;67(10):664-7. doi: 10.1136/bjo.67.10.664.
4
Effect of orally administered nadolol on the intraocular pressure in normal volunteers.口服纳多洛尔对正常志愿者眼压的影响。
Br J Ophthalmol. 1985 Jan;69(1):38-40. doi: 10.1136/bjo.69.1.38.
5
Ocular beta-blockers in glaucoma management. Clinical pharmacological aspects.青光眼治疗中的眼部β受体阻滞剂。临床药理学方面。
Drugs Aging. 1992 May-Jun;2(3):208-21. doi: 10.2165/00002512-199202030-00005.
6
Timolol: a review of its therapeutic efficacy in the topical treatment of glaucoma.
Drugs. 1979 Jan;17(1):38-55. doi: 10.2165/00003495-197917010-00002.
7
The treatment of glaucoma: role of beta-blocking agents.
Drugs. 1979 Jul;18(1):25-32. doi: 10.2165/00003495-197918010-00002.
8
[The effect of timolol and parasympathicomimetica in the treatment of the elevated intraocular pressure (author's transl)].
Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1979 Jul 2;211(1):59-66. doi: 10.1007/BF00414654.

本文引用的文献

1
Propranolol as ocular hypotensive agent.普萘洛尔作为降眼压药物。
Br J Ophthalmol. 1967 Apr;51(4):222-6. doi: 10.1136/bjo.51.4.222.
2
A comparison of the ocular hypotensive actions of salbutamol and adrenaline in chronic simple glaucoma.
Postgrad Med J. 1971 Mar;47:Suppl:122-4.
3
Effect of DL- and D-propranolol on oscular tension in rabbits and patients.DL-和D-普萘洛尔对兔及患者眼压的影响。
Exp Eye Res. 1970 Jan;9(1):82-90. doi: 10.1016/s0014-4835(70)80061-6.
4
Practolol (Eraldin) eye drops as an ocular hypotensive agent.心得宁（埃拉地平）滴眼液作为一种降眼压药物。
Br J Ophthalmol. 1973 Mar;57(3):210-4. doi: 10.1136/bjo.57.3.210.
5
Pathology of practolol-induced ocular toxicity.心得宁所致眼毒性的病理学
Br J Ophthalmol. 1976 May;60(5):312-23. doi: 10.1136/bjo.60.5.312.
6
Ocular hypotensive effect of atenolol (Tenormin, I.C.I.). A new beta-adrenergic blocker.阿替洛尔（氨酰心安，帝国化学工业公司产品）的降眼压作用。一种新型β-肾上腺素能阻滞剂。
Br J Ophthalmol. 1975 Jun;59(6):296-300. doi: 10.1136/bjo.59.6.296.
7
Proceedings: Adrenergic tachyphylaxis in animal and human eyes.
Exp Eye Res. 1975 Feb;20(2):174-5. doi: 10.1016/0014-4835(75)90157-8.
8
Atenolol versus propranolol. A comparison of ocular hypotensive effect of an oral dose.阿替洛尔与普萘洛尔。口服剂量的眼压降低效果比较。
Br J Ophthalmol. 1976 Nov;60(11):789-91. doi: 10.1136/bjo.60.11.789.
9
Effect of oral administration of various beta-blocking agents on the intraocular pressure in healthy volunteers.口服各种β受体阻滞剂对健康志愿者眼压的影响。
Exp Eye Res. 1975 Nov;21(5):451-6. doi: 10.1016/0014-4835(75)90126-8.

4%阿替洛尔滴眼液的长期降压作用。

Long-term hypotensive effect of atenolol 4% eyedrops.

作者信息

Brenkman R F

出版信息

Br J Ophthalmol. 1978 May;62(5):287-91. doi: 10.1136/bjo.62.5.287.

DOI:10.1136/bjo.62.5.287
PMID:656355
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1043215/
Abstract

The effect of long-term application of 4% atenolol eye drops has been studied in patients with either glaucoma or ocular hypertension. In some patients who show a good initial response the ocular hypotensive effect gradually wears off with long-term use. This pattern of response appears to be more frequent in patients with pretreatment intraocular pressure of 25 mmHg, or greater. In combination with atenolol miotics or adrenaline show an additive effect.

摘要

已对青光眼或高眼压症患者长期应用4%阿替洛尔滴眼液的效果进行了研究。在一些初始反应良好的患者中，长期使用后眼压降低效果会逐渐消失。这种反应模式在治疗前眼压为25 mmHg或更高的患者中似乎更常见。与阿替洛尔联合使用时，缩瞳剂或肾上腺素显示出相加作用。