Brenkman R F
Br J Ophthalmol. 1978 May;62(5):287-91. doi: 10.1136/bjo.62.5.287.
The effect of long-term application of 4% atenolol eye drops has been studied in patients with either glaucoma or ocular hypertension. In some patients who show a good initial response the ocular hypotensive effect gradually wears off with long-term use. This pattern of response appears to be more frequent in patients with pretreatment intraocular pressure of 25 mmHg, or greater. In combination with atenolol miotics or adrenaline show an additive effect.
已对青光眼或高眼压症患者长期应用4%阿替洛尔滴眼液的效果进行了研究。在一些初始反应良好的患者中,长期使用后眼压降低效果会逐渐消失。这种反应模式在治疗前眼压为25 mmHg或更高的患者中似乎更常见。与阿替洛尔联合使用时,缩瞳剂或肾上腺素显示出相加作用。