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4%阿替洛尔滴眼液的长期降压作用。

Long-term hypotensive effect of atenolol 4% eyedrops.

作者信息

Brenkman R F

出版信息

Br J Ophthalmol. 1978 May;62(5):287-91. doi: 10.1136/bjo.62.5.287.

Abstract

The effect of long-term application of 4% atenolol eye drops has been studied in patients with either glaucoma or ocular hypertension. In some patients who show a good initial response the ocular hypotensive effect gradually wears off with long-term use. This pattern of response appears to be more frequent in patients with pretreatment intraocular pressure of 25 mmHg, or greater. In combination with atenolol miotics or adrenaline show an additive effect.

摘要

已对青光眼或高眼压症患者长期应用4%阿替洛尔滴眼液的效果进行了研究。在一些初始反应良好的患者中,长期使用后眼压降低效果会逐渐消失。这种反应模式在治疗前眼压为25 mmHg或更高的患者中似乎更常见。与阿替洛尔联合使用时,缩瞳剂或肾上腺素显示出相加作用。

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本文引用的文献

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Propranolol as ocular hypotensive agent.普萘洛尔作为降眼压药物。
Br J Ophthalmol. 1967 Apr;51(4):222-6. doi: 10.1136/bjo.51.4.222.
5
Pathology of practolol-induced ocular toxicity.心得宁所致眼毒性的病理学
Br J Ophthalmol. 1976 May;60(5):312-23. doi: 10.1136/bjo.60.5.312.
7
Proceedings: Adrenergic tachyphylaxis in animal and human eyes.
Exp Eye Res. 1975 Feb;20(2):174-5. doi: 10.1016/0014-4835(75)90157-8.

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