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在大鼠再生神经肌肉接头处用局部麻醉剂阻断神经对多重神经支配演变的影响。

Consequences of blocking the nerve with a local anaesthetic on the evolution of multiinnervation at the regenerating neuromuscular junction of the rat.

作者信息

Benoit P, Changeux J P

出版信息

Brain Res. 1978 Jun 23;149(1):89-96. doi: 10.1016/0006-8993(78)90589-9.

DOI:10.1016/0006-8993(78)90589-9
PMID:656962
Abstract

A transient multiinnervation is observed in adult rats during reinnervation of the soleus muscle. Chronic blockage of the sciatic nerve with a cuff of the local anaesthetic lidocaine during reinnervation increases the number of multiply innervated muscle fibres. This result indicates that the selective elimination of redundant nerve terminals is regulated by the activity of the innervated muscle.

摘要

在成年大鼠比目鱼肌再支配过程中观察到短暂的多重神经支配。在再支配期间用局部麻醉剂利多卡因袖带对坐骨神经进行慢性阻断，会增加多重神经支配肌纤维的数量。这一结果表明，多余神经末梢的选择性消除受被支配肌肉活动的调节。

相似文献

1
Consequences of blocking the nerve with a local anaesthetic on the evolution of multiinnervation at the regenerating neuromuscular junction of the rat.在大鼠再生神经肌肉接头处用局部麻醉剂阻断神经对多重神经支配演变的影响。
Brain Res. 1978 Jun 23;149(1):89-96. doi: 10.1016/0006-8993(78)90589-9.
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