两种仓鼠巨噬细胞系的建立与鉴定
Establishment and characterization of two hamster macrophage cell lines.
作者信息
Miyoshi I, Hiraki S, Kubonishi I, Matsuda Y, Nakayama T, Kishimoto H, Masuji H, Kimura I
出版信息
Cancer Lett. 1978 May;4(5):253-7. doi: 10.1016/s0304-3835(78)94952-2.
PMID:657122
Abstract
Two hamster macrophage cell lines (HM-1 and HM-2) were established in vitro from lymphoid tumors produced in hamsters by direct implantation of normal human umbilical cord leukocytes. Despite long-term culture, both cell lines maintained the morphological, functional and surface characteristics of normal macrophages. It is considered that these cell lines were derived from host macrophages infiltrating the heterotransplants.
摘要
通过直接植入正常人脐带白细胞在仓鼠体内产生的淋巴瘤，在体外建立了两种仓鼠巨噬细胞系（HM-1和HM-2）。尽管经过长期培养，这两种细胞系仍保持正常巨噬细胞的形态、功能和表面特征。据认为，这些细胞系源自浸润异种移植的宿主巨噬细胞。
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