Unten S, Sakagami H, Konno K
Cell Differ. 1983 Feb;12(2):93-8. doi: 10.1016/0045-6039(83)90061-1.
Mouse myeloid leukemia (M1) cells were induced to differentiate in vitro by treatment with dexamethasone. After 8 h of treatment, induction of phagocytic and lysozymic activities and depression of DNA synthesis started at the same time and proceeded irreversibly. DNA synthesis in the nuclear system reflected primarily DNA replication rather than repair and this activity declined during M1 cell differentiation.
小鼠髓性白血病（M1）细胞通过地塞米松处理在体外被诱导分化。处理8小时后，吞噬活性和溶菌酶活性的诱导以及DNA合成的抑制同时开始并不可逆地进行。核系统中的DNA合成主要反映DNA复制而非修复，并且这种活性在M1细胞分化过程中下降。
