Nickerson P A, Hristić M, Pantić V
Cell Tissue Res. 1978 May 29;189(2):277-86. doi: 10.1007/BF00209277.
Maternal adrenalectomy at 7 or 14 days of gestation produced increased cell necrosis within zona reticularis cells on the day of birth and at 24 or 48 h after birth. Small remnants or large portions of adrenocortical cells were present within macrophages. In otherwise normal adrenocortical cells, lipid droplets were incorporated within some mitochondria. Autophagocytosis of single mitochondria was observed within adrenocortical cells. Undoubtedly ultrastructural changes represent stimulation of adrenocortical cells in neonatal rats in response to maternal adrenalectomy.
妊娠7天或14天时进行母体肾上腺切除术，会导致出生当天以及出生后24或48小时时，网状带细胞内的细胞坏死增加。巨噬细胞内存在小部分或大部分肾上腺皮质细胞的残余物。在其他方面正常的肾上腺皮质细胞中，一些线粒体内含有脂滴。在肾上腺皮质细胞内观察到单个线粒体的自噬现象。毫无疑问，超微结构的变化代表了新生大鼠肾上腺皮质细胞对母体肾上腺切除术的反应性刺激。
