放射性磷的经胎盘致癌作用。
Transplacental carcinogenesis with radioactive phosphorus.
作者信息
Berry C L, Amerigo J, Nickols C, Swettenham K V
出版信息
Hum Toxicol. 1983 Jan;2(1):49-62. doi: 10.1177/096032718300200104.
PMID:6573299
Abstract
1 An attempt was made to produce a model of osteogenic sarcoma using 32P transplacentally. 2 Fetal tissues appeared to be resistant to irradiation as no tumour was induced at an increased frequency in treated animals. 3 Tumours that normally occur in our strain (Sprague-Dawley rats) showed a clear tendancy to occur earlier in post-natal life in treated animals compared with controls.
摘要
- 尝试通过经胎盘给予32P来建立骨肉瘤模型。2. 胎儿组织似乎对辐射有抗性，因为在接受治疗的动物中未以更高频率诱导出肿瘤。3. 与对照组相比，我们的品系（斯普拉格-道利大鼠）中正常出现的肿瘤在接受治疗的动物的出生后生命中明显有更早出现的趋势。
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