用放射性铈诱导大鼠产生的骨肿瘤。

Delbrück H G, Allouche M, Jasmin C, Morin M, Deml F, Anghileri L, Masse R, Lafuma J

Br J Cancer. 1980 May;41(5):809-15. doi: 10.1038/bjc.1980.145.

A technique is described for the induction of metastasizing bone tumours in rats by local inoculation of 144cerium. Bone sarcomas develop in 90% of the animals and 74% of these had lung metastases. The tumours can be easily cultured and maintained by serial transplantations. Preliminary data of clinical, histological and kinetic characteristics of these bone tumours are given.

本文描述了一种通过局部接种铈-144在大鼠中诱导转移性骨肿瘤的技术。90%的动物发生骨肉瘤，其中74%有肺转移。这些肿瘤易于培养，并可通过连续传代进行维持。文中给出了这些骨肿瘤临床、组织学和动力学特征的初步数据。