Tsiapalis C M
Nature. 1977 Mar 3;266(5597):27-31. doi: 10.1038/266027a0.
Fractionation of purified avian myeloblastosis virus DNA polymerase, after phosphorylation in vitro, revealed the presence of a small acidic proten, a phosphate acceptor polypeptide with high specific activity. Its presence in the phosphorylated form with the polymerase resulted in as much as a 10-fold increase in the rate of DNA synthesis. Its presence in the dephosphorylated form with the polymerase had no effect in the rate of DNA synthesis.
体外磷酸化后对纯化的禽成髓细胞瘤病毒DNA聚合酶进行分级分离，发现存在一种小的酸性蛋白，即具有高比活性的磷酸受体多肽。它与聚合酶以磷酸化形式存在时，可使DNA合成速率提高多达10倍。它与聚合酶以去磷酸化形式存在时，对DNA合成速率没有影响。
