Petersen J, Andersen E B, Dige-Petersen H, Ahlgren P, Mortensen E L
Acta Neurol Scand Suppl. 1983;94:49-56.
In 25 patients with cerebral arteriovenous malformation (AVM) computer tomography (CT) was compared with dynamic and static intravenous radionuclide angioscintigraphy (99mTc-labelled red blood cells). The diagnosis was verified by arteriography performed 2-20 years prior to this study. Scintigrams and CT-scans were evaluated 'blindly' by independent observers after pooling of the patient studies with 20 and 20 control studies, respectively. Only images strictly characteristic of AVM were classified as positive. The nosographic sensitivity of both methods was about 70%, in a few patients they were supplementary. Neither CT nor scintigraphy were able to detect lesions of less than 2 cm diameter. The methods seem to be of equal and rather high specificity, and are both well suited as screening procedures. CT provides additional information as to other intracranial abnormalities. The screening method of first choice when AVM is suspected may be CT or angioscintigraphy, depending on availability of equipment and expertise.
对25例脑动静脉畸形（AVM）患者的计算机断层扫描（CT）与动态及静态静脉放射性核素血管闪烁造影（99mTc标记的红细胞）进行了比较。诊断通过本研究前2至20年进行的动脉造影得以证实。在分别将患者研究与20例对照研究合并后，由独立观察者“盲法”评估闪烁造影图和CT扫描图。仅将严格具有AVM特征的图像分类为阳性。两种方法的疾病诊断敏感性均约为70%，在少数患者中二者具有互补性。CT和闪烁造影均无法检测出直径小于2 cm的病变。这两种方法似乎具有同等且相当高的特异性，均非常适合作为筛查程序。CT还能提供有关其他颅内异常的额外信息。当怀疑存在AVM时，首选的筛查方法可能是CT或血管闪烁造影，具体取决于设备和专业知识的可及性。
