儿童抗菌药物处方错误

Antimicrobial prescribing errors in children.

作者信息

Grimwood K, Cook J J, Abbott G D

出版信息

N Z Med J. 1983 Oct 26;96(742):785-7.

Abstract

During a 120 day period, the charts of patients who had received antimicrobial agents were examined. This group numbered 255 and comprised 52% of children admitted with infections. Patients treated by family doctors and/or hospital staff predominantly had respiratory infections and the ampicillin/amoxycillin group of drugs was most commonly prescribed. Of the 203 antimicrobial agents prescribed by hospital staff, 64% were considered to be prescribed appropriately. The major errors related to dosage, the most potentially serious relating to the prescribing of aminoglycosides and chloramphenicol. Of the 203 antimicrobial agents prescribed for 171 children in the community, 11% were considered to be appropriately prescribed or without error. The major error was the prescribing of these drugs for syndromes of known viral aetiology. Errors were also frequent in relation to dosage, duration and choice of antimicrobial agents.

摘要

在120天的时间段内，对接受过抗菌药物治疗的患者病历进行了检查。这组患者有255人，占因感染入院儿童的52%。由家庭医生和/或医院工作人员治疗的患者主要患有呼吸道感染，最常开具的是氨苄西林/阿莫西林类药物。在医院工作人员开出的203种抗菌药物中，64%被认为开具得当。主要错误与剂量有关，最具潜在严重性的是氨基糖苷类和氯霉素的处方。在为社区中的171名儿童开出的203种抗菌药物中，11%被认为开具得当或无差错。主要错误是为已知病毒病因的综合征开具这些药物。在抗菌药物的剂量、疗程和选择方面也经常出现错误。