Israeli R, Sculsky M, Tiberin P
Arch Toxicol Suppl. 1983;6:238-43. doi: 10.1007/978-3-642-69083-9_43.
A 42-year old man sprayed Manzidan (a combined dithiocarbamate of Maneb and Zineb) on a cucumber plantation, twice during a week. Behavioural changes appeared after the first application, and loss of consciousness, convulsions and right hemiparesis after the second application with diffuse slow rhythm in the EEG. Both the behavioural and CNS symptomatology disappeared spontaneously after a few days. The previous history of the patient, the sudden appearance and spontaneous disappearance of the symptoms and a dose-response relationship strongly suggest that Maneb and Zineb were the cause of the illness.
一名42岁男子在黄瓜种植园喷洒代森锰锌（代森锰和代森锌的二硫代氨基甲酸盐混合物），一周内喷洒了两次。首次喷洒后出现行为改变，第二次喷洒后出现意识丧失、抽搐和右侧偏瘫，脑电图显示弥漫性慢节律。几天后，行为和中枢神经系统症状均自发消失。患者的既往病史、症状的突然出现和自发消失以及剂量反应关系强烈提示代森锰和代森锌是病因。
