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急性肾衰竭与代森锰(乙撑双二硫代氨基甲酸锰)暴露。

Acute renal failure and maneb (manganous ethylenebis[dithiocarbamate]) exposure.

作者信息

Koizumi A, Shiojima S, Omiya M, Nakano S, Sato N, Ikeda M

出版信息

JAMA. 1979 Dec 7;242(23):2583-5.

PMID:490886
Abstract

A 62-year-old man spread maneb on about 200 sq m of garden and subsequently was taken to the emergency clinic with complaints of oliguria, diarrhea, and hoarseness. Based on the clinicobiochemical data, he was found to have acute renal failure; the serum levels of BUN, creatinine, and potassium were 144.3 mg/dL, 14 mg/dL, and 5.8 mEq/L, respectively. The ST segment depression in V4-6, reciprocal ST segment elevation in V1-3, and inverted T waves in V5 and V6 were recorded on ECGs. Both the renal failure and the ECG abnormalities disappeared after hemodialysis. The possibility exists that the maneb caused the acute renal failure.

摘要

一名62岁男性在约200平方米的花园里撒了代森锰,随后因少尿、腹泻和声音嘶哑被送往急诊诊所。根据临床生化数据,发现他患有急性肾衰竭;血尿素氮、肌酐和钾的血清水平分别为144.3mg/dL、14mg/dL和5.8mEq/L。心电图记录显示V4 - 6导联ST段压低、V1 - 3导联ST段对应性抬高以及V5和V6导联T波倒置。血液透析后,肾衰竭和心电图异常均消失。代森锰导致急性肾衰竭的可能性是存在的。

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