无白血病性白血病性皮肤浸润：表现为图形皮肤损害的幼年型慢性粒细胞白血病。

Aleukemic leukemia cutis: juvenile chronic granulocytic leukemia presenting with figurate cutaneous lesions.

作者信息

Heskel N S, White C R, Fryberger S, Neerhout R C, Spraker M, Hanifin J M

出版信息

J Am Acad Dermatol. 1983 Sep;9(3):423-7. doi: 10.1016/s0190-9622(83)70153-2.

Abstract

We report a 3 1/2-year-old girl who developed a figurate cutaneous eruption. Distinctive findings in her skin biopsies, as well as unusual red cell characteristics, in the presence of a normal peripheral smear and bone marrow biopsy, led us to suspect the diagnosis of preleukemic juvenile type chronic granulocytic leukemia. This is the first case we know of in which this diagnosis was suspected prior to abnormal findings in the peripheral smear or bone marrow.

摘要

我们报告一名3岁半患地图状皮肤疹的女孩。在其皮肤活检中发现了独特的表现，以及异常的红细胞特征，而外周血涂片和骨髓活检均正常，这使我们怀疑其患有白血病前期幼年型慢性粒细胞白血病。这是我们所知的首例在出现外周血涂片或骨髓异常之前就怀疑该诊断的病例。