Besbeas S, Stearns M W
Dis Colon Rectum. 1978 May-Jun;21(4):266-8. doi: 10.1007/BF02586701.
Of 765 patients with disseminated metastatic carcinoma of the colon and rectum treated at Memorial Sloan-Kettering Cancer Center during the ten-year period 1960--1970, 53 (6.9 per cent) had skeletal metastases. Of these, 14 (1.8 per cent) had osseous metastases only. In one case the osseous lesion was the first symptom of a cancer of the sigmoid colon, and one patient had metastasis in the fibula from a primary rectal cancer. In our series the incidences of osseous metastases were 8.9 per cent from rectal carcinoma and 5.1 per cent from colonic carcinoma. The mean period from manifestation of skeletal metastasis to death was 13.2 months.
在1960年至1970年的十年间，纪念斯隆凯特琳癌症中心收治了765例结肠和直肠癌播散性转移癌患者，其中53例（6.9%）发生了骨转移。其中，14例（1.8%）仅有骨转移。1例骨病变是乙状结肠癌的首发症状，1例患者原发性直肠癌转移至腓骨。在我们的系列病例中，直肠癌骨转移发生率为8.9%，结肠癌为5.1%。从骨转移出现到死亡的平均时间为13.2个月。
