Lyerla T A, Fournier P C
Comp Biochem Physiol B. 1983;76(3):497-502. doi: 10.1016/0305-0491(83)90282-1.
Xanthine dehydrogenase (XDH; EC 1.2.1.37) activity in the clawed frog, Xenopus laevis, was detected in kidney tissue homogenates, but not in skin, liver, ovaries or gut tissues. The enzyme migrated as a single band of activity on both polyacrylamide and starch gel electropherograms, exhibited substrate inhibition, and did not appear developmentally until feeding larval stages. The tissue specificity, post-fertilization stage of appearance and single isozymic form make this a useful enzyme marker for further study concerning its developmental appearance and maintenance as a kidney-specific protein.
在爪蟾（非洲爪蟾）的肾组织匀浆中检测到了黄嘌呤脱氢酶（XDH；EC 1.2.1.37）活性，但在皮肤、肝脏、卵巢或肠道组织中未检测到。该酶在聚丙烯酰胺和淀粉凝胶电泳图谱上均迁移为单一活性条带，表现出底物抑制作用，并且直到幼体摄食阶段才在发育过程中出现。其组织特异性、受精后出现的阶段以及单一同工酶形式使其成为一种有用的酶标志物，可用于进一步研究其作为肾脏特异性蛋白的发育出现和维持情况。
